Advancements in Chemotherapy & Alternative Therapies

The practice of utilizing chemical therapy (Chemotherapy or Chemo) for the treatment of cancer began in the 1940’s and remains a fundamental treatment for many cancer types. Concerns over Germany’s devastating use of mustard gas during World War I, led two pharmacologists from the Yale School of Medicine, Louis S. Goodman and Alfred Gilman, to discover nitrogen mustard, as an effective treatment for cancer. Given the poisonous origin of chemotherapy, patients receiving these agents experienced severe side-effects that produced limitations on the doses and the benefits of the treatment. The ability to manage these toxicities and their negative side effects became crucial to the future success of cancer chemotherapy.