LPNV201: Treatment of Chemo Induced Nausea/Vomiting

LPNV201: Treatment of Chemo Induced Nausea/Vomiting

A Randomized, Dose-ranging, Open-label, Parallel Group Study to Assess the Efficacy, Safety and Pharmacokinetics of Palonosetron HCl Buccal Film versus IV Palonosetron 0.25 mg (ALOXI®) for the Prevention of Chemotherapy-induced Nausea and Vomiting in Cancer Patients Receiving Moderately Emetogenic Chemotherapy

Not all clinical research we do here at the Gettysburg Cancer Center is specifically for the treatment of cancer. We also conduct research on new ways to help alleviate the side effects experienced from cancer treatments to enhance a patient’s comfort and improve quality of life.

In this study we are looking at a new formulation and way of delivery of an existing drug called Aloxi (palonosetron). This commonly used drug to treat chemotherapy induced nausea and vomiting is given through an IV line before you get your chemotherapy. The new formulation of this drug is in the form of a very thin film that is placed inside the mouth on the cheek. This film fully dissolves in a few minutes. The study compares the effectiveness of the two drugs to see which is better at alleviating nausea and vomiting.

If you are interested in more information on this study, please contact us. Refer to the study by the title listed above. You can also find information on this study by going to clinicaltrials.gov website and searching for NCT04592198.