Category: Head & Neck Cancer

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BASKET Study – NC318 in Subjects with Advanced or Metastatic Solid Tumors
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BASKET Study – NC318 in Subjects with Advanced or Metastatic Solid Tumors

A Phase 1/2, Open-Label, Dose-Escalation, Safety and Tolerability Study of NC318 in Subjects with Advanced or Metastatic Solid Tumors NC318 is a monoclonal antibody, a first in class immunomedicine that targets Siglec-5 (S15). S15 suppresses the immune system, specifically T cells which fight infection and cancer. NC318 blocks the immune system suppression caused by S15...

Debio 1143-SCCHN-301
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Debio 1143-SCCHN-301

Randomized, double-blind placebo-controlled, Phase 3 study of Debio 1143 in combo with platinum-based chemo and standard fractionation IMRT in patients with locally advanced squamous cell carcinoma of the head and neck, suitable for definitive chemoradiotherapy (TrilynX). Squamous cell carcinoma of the head and neck (SCCHN) is the 6th most common cancer worldwide. More than half...

BASKET Study – Covers multiple solid tumor cancer types
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BASKET Study – Covers multiple solid tumor cancer types

An Open-label, Multicenter, Multicohort, Phase 2 Study to Evaluate Enfortumab Vedotin in Subjects with Previously Treated Locally Advanced or Metastatic Malignant Solid Tumors (EV-202) This study is designed to treat multiple solid tumor cancers. This type of study is done because of how the drug is expected to work against cancer. This study will enroll...