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Targeted Radiation Therapy Effective For Breast Cancer Patients

A new cancer research project funded by the United Kingdom is revealing some very positive results for breast cancer patients. The study (IMPORT LOW trial), led by The Institute of Cancer Research, London and the Cancer Research UK Cambridge Centre indicates that breast “cancer patients who received radiotherapy targeted at the original tumor site experience fewer side effects five years after treatment than those who have whole breast radiotherapy, and their cancer is just as unlikely to return.” The results which were recently published in The Lancet, an independent, international weekly general medical journal. “This approach could spare many women significant physical discomfort and emotional distress,” says Professor Arnie Purushotham, Cancer Research UK. “One of the challenges when treating early stage breast cancer is trying to minimize the side effects that can have a real impact on a woman’s life, without affecting the chances of curing her.”

The study included more than 2,000 women aged 50 or over who had early stage breast cancer that was at a low risk of coming back. Radiation therapy or radiotherapy uses ionizing radiation as part of cancer treatment to control or kill malignant cells. A common and effective treatment for breast cancer for many decades, large field radiotherapy is relatively painless in its application, but often the treatments produce side effects that range from low, short term to more severe, long term in nature. Depending on the intensity of the radiation, higher doses can cause varying, acute side effects for months or years following treatment. The nature, severity, and longevity of side effects depend on a number of treatment factors and the individual patient.

Precisely targeted radiation therapy can eradicate all evidence of disease in patients with cancer that has spread to only a few sites. Because radiation destroys cells, targeting the treatment to specific cancer cells limits the collateral damage to areas not affected by the cancer, reducing the side effects suffered by the patient.

The IMPROT LOW trial found that women who received partial radiotherapy reported fewer long term changes to the appearance and feel of their breast, than those who had radiotherapy to the whole breast. Dr. Charlotte Coles, Reader in Breast Radiation Oncology at Cambridge University, chief investigator for the trial and first author of the publication, said, “We started this trial because there was evidence that if someone’s cancer returns, it tends to do so close to the site of the original tumor, suggesting that some women receive unnecessary radiation to the whole breast. Now we have evidence to support the use of less, but equally effective, radiotherapy for selected patients.”

The technique, delivered by standard radiotherapy equipment, may lead to increased use of this treatment at cancer centers across the country and around the world. Professor Judith Bliss, scientific lead for the study within the Clinical Trials and Statistics Unit at The Institute of Cancer Research, London, said: “We’re delighted that the results of this trial have the potential to lead to a real change in the way selected breast cancer patients are treated.”

Gettysburg Cancer Center is actively working with researchers on clinical trials, providing alternative treatments for its patients. For more information on clinical trials at Gettysburg Cancer Center, click here.

Grateful for Getting the Care Needed for a Long Life

Receiving news that you have contracted a life-threatening disease is an experience most of us hope will never occur. Most often normal, busy everyday activities put the possibility of suffering such an experience way back in our minds, relegating the concern to the “I’ll deal with that when I’m older and more likely to be a victim of such news.”

A projected 1.6 million Americans will be diagnosed with cancer this year, each one experiencing that moment of shock and disbelief long put away in the back of the mind. But while most of us are well aware of the risk of cancer diagnosis as we progress in age, the news that it can actual happen to us usually comes with a significant dose of disbelief and surprise, and when it comes at an early, usually healthier period in life, the news can be even more emotionally difficult to negotiate.

Matt Sheads, a healthy thirty something insurance executive in a famous small town in Pennsylvania lived an active, healthy lifestyle, performing numerous marathons, playing ice hockey and coaching local youth sports programs. His active, health conscious approach to life statistically identified him as one among many like him who would most likely NOT experience the news that he had a rare (for men) breast cancer. Breast cancer in men is rare with less than one percent of cancer cases of the disease developing in a thousand men. Matt soon learned that breast cancer in men is usually detected as a hard lump located underneath the nipple and areola. Unlike women, men don’t immediately associate the discovery with breast cancer and often delay further investigation and treatment.

“When you are diagnosed with cancer, it all sets in”, says Matt.” I have an 8-year-old son and I was very scared of the possibility of not seeing him graduate from school. It was a huge shock to me, I didn’t even know men got breast cancer. Oh, my gosh, how can it happen to me? I was born and raised in Gettysburg and love the small-town feel.” It was through the local Gettysburg Cancer Center that Matt was referred to nearby Washington D.C. for treatment of his rare disease. A large University hospital, Medstar Georgetown Hospital has the small town, individualized philosophy when it comes to cancer treatment. “I felt very welcome, that I was a part of a family, I felt like I was in my home town” recounts Matt.

After surgery and treatment, the prognosis for Matt is good. His disease is in remission and requires only annual visits and evaluations. He is back to doing the things he loves; coaching his son in sports, playing hockey, running and looking forward to being at his son’s graduation. His advice to other men, “If you find a problem, you find an issue, don’t self-diagnose… go find a specialist… and have a conversation with them.” Don’t delay getting the care you need to live a long life.

To view Matt Sheads video visit  https://www.youtube.com/watch?v=PUJatsj94hQ&feature=youtu.be.